Charlotte A. Dawson

A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite

Laura-Oana Albulescu, Chunfang Xie, Stuart Ainsworth et al. · Nature Communications · 2020 · 165 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +15

Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms

Steven R. Hall, Sean A. Rasmussen, Edouard Crittenden et al. · Nature Communications · 2023 · 57 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +16

Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors

Rachel H. Clare, Charlotte A. Dawson, Adam Westhorpe et al. · Frontiers in Pharmacology · 2024 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib

Keirah E. Bartlett, Steven R. Hall, Sean A. Rasmussen et al. · Proceedings of the National Academy of Sciences · 2024 · 25 citations · Full text

Veterinary Medicine, Dermatology, Pharmacology +17

Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms

Nessrin Alomran, Patricia A. Blundell, Jaffer Alsolaiss et al. · Toxins · 2022 · 17 citations · Full text

Life Sciences, Immunology, Toxicology +15