Autophagy-dependent mechanism of genistein-mediated elimination of behavioral and biochemical defects in the rat model of sporadic Alzheimer's disease

Karolina Pierzynowska, Magdalena Podlacha, Lidia Gaffke, +6

Neuropharmacology

Cell AutophagyMitophagyAlzheimer's DiseaseSporadic AlzheimerMedicine +10

Correction of Huntington’s Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model

Karolina Pierzynowska, Lidia Gaffke, Aleksandra Hać, +4

NeuroMolecular Medicine

MitophagyHuntingtin ProteinGeneticsCell DeathMutated Huntingtin Aggregates +15

Age-dependent effects of dimethyl fumarate on cognitive and neuropathological features in the streptozotocin-induced rat model of Alzheimer’s disease

Irena Majkutewicz, E. Kurowska, Magdalena Podlacha, +5

Brain Research

Neurodegenerative DiseasesAge-dependent EffectsAlzheimer's DiseaseAgingMedicine +9

Underestimated Aspect of Mucopolysaccharidosis Pathogenesis: Global Changes in Cellular Processes Revealed by Transcriptomic Studies

Lidia Gaffke, Karolina Pierzynowska, Magdalena Podlacha, +5

International Journal of Molecular Sciences

Transcriptomic StudiesPathologyTranscriptomics TechnologyGene CharacterizationDisease Gene Identification +16

Antibacterial, Antifungal and Anticancer Activities of Compounds Produced by Newly Isolated Streptomyces Strains from the Szczelina Chochołowska Cave (Tatra Mountains, Poland)

Weronika Jaroszewicz, Patrycja Bielańska, Daria Lubomska, +9

Antibiotics

Proteasome Composition and Activity Changes in Cultured Fibroblasts Derived From Mucopolysaccharidoses Patients and Their Modulation by Genistein

Karolina Pierzynowska, Lidia Gaffke, Elżbieta Jankowska, +5

Frontiers in Cell and Developmental Biology

Bacteriophage DNA induces an interrupted immune response during phage therapy in a chicken model

Magdalena Podlacha, Lidia Gaffke, Łukasz Grabowski, +6

Nature Communications

Genistein induces degradation of mutant huntingtin in fibroblasts from Huntington’s disease patients

Karolina Pierzynowska, Lidia Gaffke, Zuzanna Cyske, +1

Metabolic Brain Disease

Cell AutophagyNeurodegenerative DiseasesMitophagyHd PhenotypeGenetic Disorder +12

Expression of genes involved in apoptosis is dysregulated in mucopolysaccharidoses as revealed by pilot transcriptomic analyses

Joanna Brokowska, Karolina Pierzynowska, Lidia Gaffke, +2

Cell Biology International

Transcriptomic Changes Related to Cellular Processes with Particular Emphasis on Cell Activation in Lysosomal Storage Diseases from the Group of Mucopolysaccharidoses

Estera Rintz, Lidia Gaffke, Magdalena Podlacha, +4

International Journal of Molecular Sciences