Lilli Petruzzelli

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

A Ullrich, Jeffrey R. Bell, E. Y. Chen et al. · Nature · 1985 · 2.3K citations

Insulin Resistance, Metabolic Syndrome, Insulin Signaling +12

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

Jun Liu, Shifeng Pan, Mindy H. Hsieh et al. · Proceedings of the National Academy of Sciences · 2013 · 819 citations · Full text

Wnt Signaling, Tumor Biology, Signaling Pathway +19

The allosteric inhibitor ABL001 enables dual targeting of BCR–ABL1

Andrew A. Wylie, Joseph Schoepfer, Wolfgang Jahnke et al. · Nature · 2017 · 574 citations

Molecular Pharmacology, Drug Target, Medicine +3

Phosphorylation activates the insulin receptor tyrosine protein kinase.

O M Rosen, Román Herrera, Y Olowe et al. · Proceedings of the National Academy of Sciences · 1983 · 557 citations · Full text

Insulin Receptor, Insulin Signaling, Receptor Tyrosine Kinase +17

Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.

Lilli Petruzzelli, S Ganguly, Carolyn J. Smith et al. · Proceedings of the National Academy of Sciences · 1982 · 286 citations

3T3-l1 Adipocytes, Tyrosine-specific Protein Kinase, Insulin Receptor +19