George Vielhauer

Engineering an Antibiotic to Fight Cancer: Optimization of the Novobiocin Scaffold to Produce Anti-proliferative Agents

Huiping Zhao, Alison C. Donnelly, Bhaskar Reddy Kusuma et al. · Journal of Medicinal Chemistry · 2011 · 162 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

The Design, Synthesis, and Evaluation of Coumarin Ring Derivatives of the Novobiocin Scaffold that Exhibit Antiproliferative Activity

Alison C. Donnelly, Jared R. Mays, Joseph A. Burlison et al. · The Journal of Organic Chemistry · 2008 · 153 citations · Full text

Medicine, Oncology, Pharmacology +10

Development of Novobiocin Analogues That Manifest Anti-proliferative Activity against Several Cancer Cell Lines

Joseph A. Burlison, Christopher Avila, George Vielhauer et al. · The Journal of Organic Chemistry · 2008 · 134 citations

Medicine, Medicinal Chemistry, Pharmacology +11

KU135, a Novel Novobiocin-Derived C-Terminal Inhibitor of the 90-kDa Heat Shock Protein, Exerts Potent Antiproliferative Effects in Human Leukemic Cells

Shary N. Shelton, Mary E. Shawgo, Shawna B. Matthews et al. · Molecular Pharmacology · 2009 · 96 citations · Full text

Medicine, Oncology, Pharmacology +13

Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells

Jeffery D. Eskew, Takrima Sadikot, Pedro Jorge Cortes Morales et al. · BMC Cancer · 2011 · 94 citations · Full text

Medicine, Oncology, Pharmacology +11