Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling

Yoshito Yamashiro, Bui Quoc Thang, Karina Ramírez, +7

Proceedings of the National Academy of Sciences

Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm in Mouse and Humans

Yoshito Yamashiro, Bui Quoc Thang, Seung Jae Shin, +11

Circulation Research

Loss of fibulin-4 disrupts collagen synthesis and maturation: implications for pathology resulting from<i>EFEMP2</i>mutations

Christina L. Papke, Jun Tsunezumi, Léa‐Jeanne Ringuette, +7

Human Molecular Genetics

MechanobiologyCollagen MaturationFibrosisGeneticsElastin Cross-linking +11

Angiotensin-Converting Enzyme–Induced Activation of Local Angiotensin Signaling Is Required for Ascending Aortic Aneurysms in Fibulin-4–Deficient Mice

Jianbin Huang, Yoshito Yamashiro, Christina L. Papke, +7

Science Translational Medicine

Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice

Yoshito Yamashiro, Christina L. Papke, Jungsil Kim, +7

Science Signaling

Vascular DiseaseCofilin ActivationCytoskeletonAortic AneurysmsCardiovascular Function +22

Proteomic analysis of rat retina in a steroid-induced ocular hypertension model: Potential vulnerability to oxidative stress

Nariko Miyara, Manabu Shinzato, Yoshito Yamashiro, +3

Japanese Journal of Ophthalmology

Potential VulnerabilityOcular DiseaseRetinaBiochemistryOphthalmology +11

MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1

Hideo Nonaka, Kimiko Takei, Masato Umikawa, +9

Biochemical and Biophysical Research Communications

Rap2 EffectorProtein FunctionSignal TransductionSignaling PathwayMolecular Biology +4

Rap2 function requires palmitoylation and recycling endosome localization

Yukiko Uechi, Maitsetseg Bayarjargal, Masato Umikawa, +8

Biochemical and Biophysical Research Communications

MedicineNatural SciencesRap2 FunctionEndocytic PathwayIntracellular Trafficking +4

Raman microspectroscopy and Raman imaging reveal biomarkers specific for thoracic aortic aneurysms

Kaori Sugiyama, Julia Marzi, J. Alber�, +6

Cell Reports Medicine

Reveal BiomarkersHealth SciencesMedical ImagingCardiovascular DiseaseThoracic Aortic Aneurysms +8

Proteomic Analysis of the Trabecular Meshwork of Rats in a Steroid-Induced Ocular Hypertension Model: Downregulation of Type I Collagen C-Propeptides

Manabu Shinzato, Yoshito Yamashiro, Nariko Miyara, +6

Ophthalmic Research