Tanesha C. Osborne

Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3

Bryan Knuckley, Corey P. Causey, Justin E. Jones et al. · Biochemistry · 2010 · 176 citations

Immunology, Selective Inhibitors, Enzymatic Modification +23

Protein Arginine Methyltransferase 1:  Positively Charged Residues in Substrate Peptides Distal to the Site of Methylation Are Important for Substrate Binding and Catalysis

Tanesha C. Osborne, Obiamaka Obianyo, Xing Zhang et al. · Biochemistry · 2007 · 134 citations · Full text

Histone Modifications, Epigenetic Change, Molecular Biology +24

In Situ Generation of a Bisubstrate Analogue for Protein Arginine Methyltransferase 1

Tanesha C. Osborne, Rachel L. Weller Roska, Scott R. Rajski et al. · Journal of the American Chemical Society · 2008 · 92 citations

Molecular Biology, Bisubstrate Analogue, Novel Prmt Substrates +18

Kinetic Mechanism of Protein Arginine Methyltransferase 1

Obiamaka Obianyo, Tanesha C. Osborne, Paul R. Thompson · Biochemistry · 2008 · 77 citations · Full text

Molecular Biology, Chemical Biology, Kinetic Mechanism +17

A Chloroacetamidine‐Based Inactivator of Protein Arginine Methyltransferase 1: Design, Synthesis, and In Vitro and In Vivo Evaluation

Obiamaka Obianyo, Corey P. Causey, Tanesha C. Osborne et al. · ChemBioChem · 2010 · 42 citations · Full text