Dan Lohse

Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression

Omar D. Perez, Christopher R. Logg, Kei Hiraoka et al. · Molecular Therapy · 2012 · 137 citations · Full text

Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infarction

Moorthy S. S. Palanki, Elena Dneprovskaia, John Doukas et al. · Journal of Medicinal Chemistry · 2007 · 55 citations · Full text

Pi3k Inhibitors, Cardiovascular Pharmacology, Pharmacotherapy +16

Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays

Glenn Noronha, Kathy Barrett, Antonio Boccia et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 46 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +13

Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration

Moorthy S. S. Palanki, Hideo Akiyama, Peter A. Campochiaro et al. · Journal of Medicinal Chemistry · 2008 · 44 citations · Full text

Inhibitors of ABL and the ABL-T315I Mutation

Glenn Noronha, Jianguo Cao, Chun P. Chow et al. · Current Topics in Medicinal Chemistry · 2008 · 41 citations