Concepedia

Niklas Jänsch

NJ

Statistics

Publications

10

Citations

289

H-Index

10

Active since

2018

Affiliations

Technische Universität Darmstadt(Current)

Bharati Vidyapeeth Deemed University

University Hospital Heidelberg

HUN-REN Research Centre for Natural Sciences

German Cancer Research Center

Niklas Jänsch is an author at Technische Universität Darmstadt specializing in enzyme inhibition, medicinal chemistry, and drug discovery.

Publications per year

2018–2023

10

Publications

10

Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation

Neha Upadhyay, Kalpana Tilekar, Niklas Jänsch et al. · Bioorganic Chemistry · 2020 · 51 citations · Full text

, , +13

The enzyme activity of histone deacetylase 8 is modulated by a redox-switch

Niklas Jänsch, Christian Meyners, Marius Muth et al. · Redox Biology · 2018 · 49 citations · Full text

, , +16

Discovery of 5-naphthylidene-2,4-thiazolidinedione derivatives as selective HDAC8 inhibitors and evaluation of their cytotoxic effects in leukemic cell lines

Kalpana Tilekar, Neha Upadhyay, Niklas Jänsch et al. · Bioorganic Chemistry · 2019 · 47 citations

, , +5

Thiocarbonyl Surrogate via Combination of Potassium Sulfide and Chloroform for Dithiocarbamate Construction

Wei Tan, Niklas Jänsch, Tina Öhlmann et al. · Organic Letters · 2019 · 35 citations

, , +12

Synthesis and structure activity relationship of 1, 3-benzo-thiazine-2-thiones as selective HDAC8 inhibitors

Benjamin Wolff, Niklas Jänsch, Wisely Oki Sugiarto et al. · European Journal of Medicinal Chemistry · 2019 · 29 citations · Full text

, , +13

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