Simon Sharpe

Structure of an Intermediate State in Protein Folding and Aggregation

Philipp Neudecker, Paul Robustelli, Andrea Cavalli et al. · Science · 2012 · 403 citations

Protein Assembly, Molecular Biology, Fibrillar Aggregates +19

Direct observation of structure and dynamics during phase separation of an elastomeric protein

Sean E. Reichheld, Lisa D. Muiznieks, Fred W. Keeley et al. · Proceedings of the National Academy of Sciences · 2017 · 266 citations · Full text

Core Structure of Amyloid Fibrils Formed by Residues 106–126 of the Human Prion Protein

P.J. Walsh, Karen Simonetti, Simon Sharpe · Structure · 2009 · 98 citations · Full text

Amyloid Fibrils Formed, Protein Function, Biochemistry +10

Positive Charge Patterning and Hydrophobicity of Membrane-Active Antimicrobial Peptides as Determinants of Activity, Toxicity, and Pharmacokinetic Stability

Tracy A. Stone, Gregory B. Cole, Dorna Ravamehr-Lake et al. · Journal of Medicinal Chemistry · 2019 · 75 citations

The Mechanism of Membrane Disruption by Cytotoxic Amyloid Oligomers Formed by Prion Protein(106–126) Is Dependent on Bilayer Composition

P.J. Walsh, Gillian Vanderlee, Jason Yau et al. · Journal of Biological Chemistry · 2014 · 71 citations · Full text

Proteinlipid Interaction, Membrane Disruption, Bilayer Composition +10