Concepedia
Statistics
Publications
8
Citations
199
H-Index
Active since
2016
Affiliations
Moffitt Cancer Center(Current)
University of South Florida
University of Minnesota
Innovative Design Labs (United States)
Rezaul M. Karim is an author at Moffitt Cancer Center specializing in medicinal chemistry, drug discovery, and medicine.
Top concepts
MedicineDrug DiscoveryMedicinal ChemistryBiochemistryPharmacologyNatural SciencesMolecular BiologySmall MoleculesSystems BiologyChemical Biology
Publications per year
2016–2022
Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon
Afua A. Akuffo, Aileen Y. Alontaga, Rainer Metcalf et al. · Journal of Biological Chemistry · 2018 · 49 citations · Full text
Targeting the BRD4-HOXB13 Coregulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer
Niveditha Nerlakanti, Jiqiang Yao, Duy T. Nguyen et al. · Molecular Cancer Therapeutics · 2018 · 35 citations · Full text
Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains
Rezaul M. Karim, A. Chan, J. Zhu et al. · Journal of Medicinal Chemistry · 2020 · 30 citations · Full text
Inhibitor Selectivity, Molecular Biology, Protein 9 +21
Discovery of Dual TAF1-ATR Inhibitors and Ligand-Induced Structural Changes of the TAF1 Tandem Bromodomain
Rezaul M. Karim, Leixiang Yang, Lihong Chen et al. · Journal of Medicinal Chemistry · 2022 · 23 citations · Full text
Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors
Rezaul M. Karim, Melissa J. Bikowitz, A. Chan et al. · Journal of Medicinal Chemistry · 2021 · 22 citations · Full text
Drug Target, Kinase Inhibitors, Molecular Biology +17
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