Simvastatin and Niacin, Antioxidant Vitamins, or the Combination for the Prevention of Coronary Disease

Bryan Brown, Xue-Qiao Zhao, Alan Chait, +14

New England Journal of Medicine

Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

Tomáš Vaisar, Subramaniam Pennathur, Pattie S. Green, +18

Journal of Clinical Investigation

Healthy SubjectsProtease InhibitionImmunologyMolecular BiologyInflammation +18

Vascular cell adhesion molecule-1 is expressed in human coronary atherosclerotic plaques. Implications for the mode of progression of advanced coronary atherosclerosis.

Kevin D. O’Brien, Margaret D. Allen, Thomas O. McDonald, +7

Journal of Clinical Investigation

Neovascular Expression of E-Selectin, Intercellular Adhesion Molecule-1, and Vascular Cell Adhesion Molecule-1 in Human Atherosclerosis and Their Relation to Intimal Leukocyte Content

Kevin D. O’Brien, Thomas O. McDonald, Alan Chait, +2

Circulation

Susceptibility of small, dense, low-density lipoproteins to oxidative modification in subjects with the atherogenic lipoprotein phenotype, pattern B

Alan Chait, Ronald Brazg, Diane L. Tribble, +1

The American Journal of Medicine

Metabolic SyndromePattern BCardiovascular DiseaseBiochemistryLipid Peroxidation +12

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture.

Jay W. Heinecke, H. R. Rosen, Alan Chait

Journal of Clinical Investigation

Vascular DiseaseIron MetabolismLipid PeroxidationLow DensityRedox Biology +15

Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells.

Jay W. Heinecke, L. Baker, H. R. Rosen, +1

Journal of Clinical Investigation

Lipid PeroxidationRedox BiologyOxidative StressSuperoxide DismutaseDyslipidemia +15

The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells.

Jay W. Heinecke, H. R. Rosen, Lucy A. Suzuki, +1

Journal of Biological Chemistry

Lipid PeroxidationRedox BiologyCellular PhysiologyOxidative StressSuperoxide Dismutase +16

Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)

Scott M. Grundy, David W. Bilheimer, Alan Chait, +25

JAMA

Metabolic SyndromeHypertensionSecond ReportPrimary PreventionCardiovascular Disease +10

The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport

Constanze Bergt, Subramaniam Pennathur, Xiaoyun Fu, +10

Proceedings of the National Academy of Sciences

Human Artery WallLipid PeroxidationImmunologyPlasma HdlHyperlipidemia +15