Reversal of RNA Dominance by Displacement of Protein Sequestered on Triplet Repeat RNA

Thurman M. Wheeler, Krzysztof Sobczak, John D. Lueck, +4

Science

GeneticsMolecular BiologyMolecular GeneticsProtein SequesteredLong Non-coding Rna +17

Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1

Takashi Kimura, Masayuki Nakamori, John D. Lueck, +7

Human Molecular Genetics

Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy

Thurman M. Wheeler, John D. Lueck, Maurice S. Swanson, +2

Journal of Clinical Investigation

Muscle FunctionEngineeringPathologyMolecular BiologyCytoskeleton +14

Heat‐ and anesthesia‐induced malignant hyperthermia in an RyR1 knock‐in mouse

Mihail G. Chelu, Sanjeewa A. Goonasekera, William J. Durham, +8

The FASEB Journal

MechanobiologyMalignant HyperthermiaMuscle FunctionDevelopmental BiologyMolecular Physiology +11

Engineered transfer RNAs for suppression of premature termination codons

John D. Lueck, Jae Seok Yoon, Alfredo Perales‐Puchalt, +8

Nature Communications

Muscle Chloride Channel Dysfunction in Two Mouse Models of Myotonic Dystrophy

John D. Lueck, Ami Mankodi, Maurice S. Swanson, +2

The Journal of General Physiology

Genetic ablation of complement C3 attenuates muscle pathology in dysferlin-deficient mice

Renzhi Han, Ellie Frett, Jennifer Lévy, +8

Journal of Clinical Investigation

ImmunologyImmune SystemImmunogeneticsSkeletal MuscleCell Signaling +16

Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1

John D. Lueck, Codrin Lungu, Ami Mankodi, +4

American Journal of Physiology-Cell Physiology

Muscle FunctionPathologyChloride ChannelopathyChloride ConductanceCellular Physiology +22

Efficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs

Wooree Ko, Joseph J. Porter, Matthew T. Sipple, +2

Molecular Therapy — Nucleic Acids

EngineeringAnticodon-engineered Transfer RnasMedicineGeneticsRna Biology +7

Mouse fukutin deletion impairs dystroglycan processing and recapitulates muscular dystrophy

Aaron M. Beedle, Amy Turner, Yoshiaki Saito, +5

Journal of Clinical Investigation

Knockout MouseGene DeletionNeurodegenerative DiseasesDevelopmental BiologyTissue Development +13