Tomokazu Ohnuma

Reverse geometrical selectivity in glucuronidation and sulfation of cis- and trans-4-hydroxytamoxifens by human liver UDP-glucuronosyltransferases and sulfotransferases

Takahito Nishiyama, Kenichiro Ogura, Hiroaki Nakano et al. · Biochemical Pharmacology · 2002 · 107 citations

Medicine, Biochemistry, Pharmacology +14

Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4

Teppei Kaku, Kenichiro Ogura, Takahito Nishiyama et al. · Biochemical Pharmacology · 2004 · 71 citations

Life Sciences, Biochemistry, Pharmacology +14

Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound

Tomokazu Ohnuma, Shinji Nakayama, Eisaburo Anan et al. · Toxicology and Applied Pharmacology · 2009 · 68 citations

Life Sciences, Molecular Biology, Pharmacology +14

Dihydropyrimidine Dehydrogenase Activity in 150 Healthy Japanese Volunteers and Identification of Novel Mutations

Kenichiro Ogura, Tomokazu Ohnuma, Yoshiyuki Minamide et al. · Clinical Cancer Research · 2005 · 58 citations

Life Sciences, Genetics, Molecular Genetics +13

Enhanced sensitivity of A549 cells to the cytotoxic action of anticancer drugs via suppression of Nrf2 by procyanidins from Cinnamomi Cortex extract

Tomokazu Ohnuma, Takashi Matsumoto, Ayano Itoi et al. · Biochemical and Biophysical Research Communications · 2011 · 54 citations

Medicine, Oncology, Pharmacology +12