Jeffrey R. Holt

TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells

David P. Corey, Jaime Garcı́a-Añoveros, Jeffrey R. Holt et al. · Nature · 2004 · 725 citations

Natural Sciences, Biophysics, Physiology +13

Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents

Xue Gao, Yong Tao, Verónica Lamas et al. · Nature · 2017 · 541 citations · Full text

Medicine, Genetics, Molecular Genetics +12

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

Yoshiyuki Kawashima, Gwenaëlle S. G. Géléoc, Kiyoto Kurima et al. · Journal of Clinical Investigation · 2011 · 461 citations · Full text

Life Sciences, Neuroscience, Physiology +17

TMC1 and TMC2 Are Components of the Mechanotransduction Channel in Hair Cells of the Mammalian Inner Ear

Bifeng Pan, Gwenaëlle S. G. Géléoc, Yukako Asai et al. · Neuron · 2013 · 447 citations · Full text

Life Sciences, Neuroscience, Physiology +17

TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells

Bifeng Pan, Nurunisa Akyuz, Xiaoping Liu et al. · Neuron · 2018 · 370 citations · Full text

Life Sciences, Neuroscience, Otolaryngology +16