Single-molecule visualization of DNA G-quadruplex formation in live cells

Marco Di Antonio, Aleks Ponjavic, Antanas Radzevičius, +8

Nature Chemistry

Single-molecule VisualizationMolecular Biological MethodNatural SciencesDna AnalysisDna Replication +3

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle

Philip J. M. Brouwer, Aleksandar Antanasijevic, Zachary T. Berndsen, +28

Nature Communications

Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C

Mei Zeng, Jia Lu, Lianbo Li, +16

Cell chemical biology

Medicinal ChemistryKras G12cMedicinePharmacotherapyDrug Development +4

Affinity Enhancement of Protein Ligands by Reversible Covalent Modification of Neighboring Lysine Residues

Alberto Dal Corso, Marco Catalano, Anja Schmid, +2

Angewandte Chemie International Edition

Drug TargetProtein TargetMolecular BiologyProtein LigandsAffinity Enhancement +15

A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks

Gabriele Bassi, Nicholas Favalli, Miriam Vuk, +13

Advanced Science

Modular AssemblyBuilding BlocksBioorganic ChemistryEngineeringMolecular Biology +17

Affinity Selections of DNA‐Encoded Chemical Libraries on Carbonic Anhydrase IX‐Expressing Tumor Cells Reveal a Dependence on Ligand Valence

Sebastian Oehler, Marco Catalano, Ilario Scapozza, +7

Chemistry - A European Journal

Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format

Gabriele Bassi, Nicholas Favalli, Sebastian Oehler, +4

Biochemical and Biophysical Research Communications

EngineeringDna AnalysisMolecular BiologyDna NanotechnologyDouble-stranded Format +14

Selective Fragments for the CREBBP Bromodomain Identified from an Encoded Self‐assembly Chemical Library

Marco Catalano, Mustafa Moroglu, Petra E. M. Balbi, +7

ChemMedChem

Affinity Enhancement of Protein Ligands by Reversible Covalent Modification of Neighboring Lysine Residues

Alberto Dal Corso, Marco Catalano, Anja Schmid, +2

Angewandte Chemie

Drug TargetProtein TargetMolecular BiologyProtein LigandsAffinity Enhancement +15

Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands

Marco Catalano, Sebastian Oehler, Luca Prati, +4

Analytical Chemistry