Charlene Smith-Geater

An RNA-targeting CRISPR–Cas13d system alleviates disease-related phenotypes in Huntington’s disease models

Kathryn H. Morelli, Qian Wu, Maya L. Gosztyla et al. · Nature Neuroscience · 2022 · 103 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation

Charlene Smith-Geater, Sarah Hernandez, Ryan G. Lim et al. · Stem Cell Reports · 2020 · 79 citations · Full text

Life Sciences, Developmental Biology, Neuroscience +17

CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons

Gong‐Her Wu, Charlene Smith-Geater, Jesús G. Galaz-Montoya et al. · Nature Communications · 2023 · 64 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington’s disease

Eva L. Morozko, Charlene Smith-Geater, Alejandro Mas Monteys et al. · Proceedings of the National Academy of Sciences · 2021 · 54 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice

Gema M. Olivarria, Susana Furman, Collin Pachow et al. · Journal of Virology · 2021 · 31 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17