Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

Wanting He, Haoqiang Wan, Lichen Hu, +6

Cell Research

RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis

Zhentao Yang, Yan Wang, Yingying Zhang, +9

Nature Cell Biology

BiochemistryMitochondrial FunctionPhysiologyApoptosisCell Death +10

RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice

Zhe Huang, Suqin Wu, Yaoji Liang, +12

Cell Host & Microbe

Viral ReplicationMolecular VirologyHsv-1 Icp6PathogenesisViral Pathogenesis +8

Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling

Wanze Chen, Zhenru Zhou, Lisheng Li, +9

Journal of Biological Chemistry

Ppm1b negatively regulates necroptosis through dephosphorylating Rip3

Wanze Chen, Jianfeng Wu, Lisheng Li, +15

Nature Cell Biology

Signal TransductionApoptosisCell DeathMedicineCell Biology +2

RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes

Xiang Li, Chuan‐Qi Zhong, Rui Wu, +14

Protein & Cell

Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination

Zhixiong Liu, Minbiao Yan, Yaoji Liang, +13

Neuron

Neurodegenerative DiseasesNeuroregenerationMolecular NeuroscienceMolecular BiologyOligodendrocyte Differentiation +6

Investigation of Receptor interacting protein (RIP3)-dependent Protein Phosphorylation by Quantitative Phosphoproteomics

Xiurong Wu, Lili Tian, Jie Li, +11

Molecular & Cellular Proteomics

A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade

Zhang‐Hua Yang, Xiaonan Wu, Peng He, +11

Molecular Cell

InflammationSignal TransductionSignaling PathwayApoptosisImmunology +6

TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activation

Xudong Wang, Yu Gong, Zhilong Chen, +9

Nature Immunology

T Cell ActivationSynaptic PlasticitySignal TransductionSignaling PathwaySynaptic Signaling +11