A Shenton

Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: a report of 121 families with proven mutations

E. Barrow, Lee Robinson, Waleed Alduaij et al. · Clinical Genetics · 2009 · 317 citations

Medicine, Genetics, Oncology +17

Women with neurofibromatosis 1 are at a moderately increased risk of developing breast cancer and should be considered for early screening

S. Sharif, Anthony Moran, S M Huson et al. · Journal of Medical Genetics · 2007 · 242 citations · Full text

Medicine, Oncology, Cancer Epidemiology +14

Penetrance estimates for BRCA1 and BRCA2based on genetic testing in a Clinical Cancer Genetics service setting: Risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

D. Gareth Evans, A Shenton, Emma R. Woodward et al. · BMC Cancer · 2008 · 224 citations · Full text

Life Sciences, Genetics, Oncology +17

Predicting the likelihood of carrying a <i>BRCA1</i> or <i>BRCA2</i> mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics

Antonis C. Antoniou, Rachel Hardy, Lyndon Walker et al. · Journal of Medical Genetics · 2008 · 195 citations

Life Sciences, Genetics, Molecular Genetics +17

BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives

Fiona Lalloo, Jennifer M. Varley, Anthony Moran et al. · European Journal of Cancer · 2006 · 175 citations

Life Sciences, Genetics, Oncology +16