Joel D. Parry

Doxorubicin In Vivo Rapidly Alters Expression and Translation of Myocardial Electron Transport Chain Genes, Leads to ATP Loss and Caspase 3 Activation

Amy Pointon, Tracy Walker, Kate Phillips et al. · PLoS ONE · 2010 · 127 citations · Full text

<i>In silico</i>and<i>in vitro</i>evaluation of exonic and intronic off-target effects form a critical element of therapeutic ASO gapmer optimization

Piotr J. Kamola, Jeremy Kitson, Gemma Turner et al. · Nucleic Acids Research · 2015 · 106 citations · Full text

Critical Element, Molecular Biology, Intronic Off-target Effects +18

Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses

Ben Forbes, Raegan O’Lone, Philippa Pribul Allen et al. · Advanced Drug Delivery Reviews · 2014 · 90 citations · Full text

Inflammation, Macrophage Biology, Asthma +15

Strategies for In Vivo Screening and Mitigation of Hepatotoxicity Associated with Antisense Drugs

Piotr J. Kamola, Klio Maratou, Paul A. Wilson et al. · Molecular Therapy — Nucleic Acids · 2017 · 58 citations · Full text

Immunology, Toxicology, Hepatotoxicity +16

Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis

Kenneth L. Clark, Stephen Hughes, Pallav A. Bulsara et al. · Molecular Therapy — Nucleic Acids · 2013 · 35 citations · Full text