Theodosia A. Kalfa

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia—TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial

Russell E. Ware, Barry R. Davis, William H. Schultz et al. · The Lancet · 2015 · 514 citations · Full text

Medicine, Hematology, Pediatrics +12

Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection

Shokrollah Elahi, James M. Ertelt, Jeremy M. Kinder et al. · Nature · 2013 · 420 citations

Life Sciences, Cell Biology, Immunology +14

Base editing of haematopoietic stem cells rescues sickle cell disease in mice

Gregory A. Newby, Jonathan Yen, Kaitly J. Woodard et al. · Nature · 2021 · 380 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease

Alex George, Suvarnamala Pushkaran, Diamantis G. Konstantinidis et al. · Blood · 2013 · 204 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Unrestrained erythroblast development in Nix ^−/− mice reveals a mechanism for apoptotic modulation of erythropoiesis

Abhinav Diwan, Andrew G. Koesters, Amy Odley et al. · Proceedings of the National Academy of Sciences · 2007 · 145 citations · Full text

Life Sciences, Cell Biology, Hematology +17