Mike Birch

F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase

Jason D. Oliver, Graham E. M. Sibley, Nicola Beckmann et al. · Proceedings of the National Academy of Sciences · 2016 · 282 citations · Full text

Life Sciences, Microbiology, Pharmacology +17

Effect of the Novel Antifungal Drug F901318 (Olorofim) on Growth and Viability of Aspergillus fumigatus

Saskia du Pré, Nicola Beckmann, Mariana Cruz Almeida et al. · Antimicrobial Agents and Chemotherapy · 2018 · 110 citations · Full text

Life Sciences, Microbiology, Pharmacology +17

In vitro activity of the novel antifungal compound F901318 against difficult-to-treat Aspergillus isolates

Jochem B. Buil, Antonius J. M. M. Rijs, Jacques F. Meis et al. · Journal of Antimicrobial Chemotherapy · 2017 · 102 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Evidence of multiple extracellular phospholipase activities of Aspergillus fumigatus

Mike Birch, G. D. Robson, D. Law et al. · Infection and Immunity · 1996 · 88 citations · Full text

Life Sciences, Biochemistry, Microbiology +16

Aspergillus fumigatus strains that evolve resistance to the agrochemical fungicide ipflufenoquin in vitro are also resistant to olorofim

Norman van Rhijn, Isabelle S. R. Storer, Mike Birch et al. · Nature Microbiology · 2023 · 72 citations · Full text

Life Sciences, Microbiology, Microbial Genetics +16