Aparna Shekar

Rare Autism-Associated Variants Implicate Syntaxin 1 (STX1 R26Q) Phosphorylation and the Dopamine Transporter (hDAT R51W) in Dopamine Neurotransmission and Behaviors

Etienne Cartier, Peter J. Hamilton, Andrea N. Belovich et al. · EBioMedicine · 2015 · 78 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in <i>SLC6A3</i>

Nicholas G. Campbell, Aparna Shekar, Jenny I. Aguilar et al. · Proceedings of the National Academy of Sciences · 2019 · 42 citations · Full text

Life Sciences, Genetics, Neuroscience +17

A network of phosphatidylinositol (4,5)-bisphosphate (PIP2) binding sites on the dopamine transporter regulates amphetamine behavior in Drosophila Melanogaster

Andrea N. Belovich, Jenny I. Aguilar, Samuel J. Mabry et al. · Molecular Psychiatry · 2019 · 41 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease

Freja Herborg, Kathrine L. Jensen, Sasha Tolstoy et al. · JCI Insight · 2021 · 21 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Zn2+ reverses functional deficits in a de novo dopamine transporter variant associated with autism spectrum disorder

Peter J. Hamilton, Aparna Shekar, Andrea N. Belovich et al. · Molecular Autism · 2015 · 20 citations · Full text

Life Sciences, Genetics, Neuroscience +15