Shannon E. McGettigan

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Omkar U. Kawalekar, Roddy S. O’Connor, Joseph A. Fraietta et al. · Immunity · 2016 · 1.1K citations · Full text

Car T Cells, Molecular Physiology, Signal Transduction +14

Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

Sònia Guedan, Avery D. Posey, Carolyn E. Shaw et al. · JCI Insight · 2018 · 563 citations · Full text

Icos Icd, Cell Therapy, Cancer Immunosurveillance +15

Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia

Joseph A. Fraietta, Kyle A. Beckwith, Prachi Patel et al. · Blood · 2016 · 450 citations · Full text

Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma

Laura A. Johnson, John Scholler, Takayuki Ohkuri et al. · Science Translational Medicine · 2015 · 448 citations · Full text

Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer

Julia Tchou, Yangbing Zhao, Bruce L. Levine et al. · Cancer Immunology Research · 2017 · 435 citations