Lise Vanderlynden

GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma <i>via</i> modulation of lysosomal functions

Sonia Brun, Eloïne Bestion, Éric Raymond et al. · Autophagy · 2021 · 86 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases

Yveline Hamon, Monika Łęgowska, Virginie Hervé et al. · Journal of Biological Chemistry · 2016 · 68 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L

Ahlame Saidi, Mariana Kasabova, Lise Vanderlynden et al. · Scientific Reports · 2019 · 47 citations · Full text

Medicine, Molecular Medicine, Pharmacology +13

Analysis of urinary cathepsin C for diagnosing Papillon–Lefèvre syndrome

Yveline Hamon, Monika Łęgowska, Patricia Fergelot et al. · FEBS Journal · 2015 · 16 citations · Full text

Medicine, Pathobiology, Pathology +13

GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition

Eloïne Bestion, Zuzana Macek Jílková, Jean‐Louis Mège et al. · Therapeutic Advances in Chronic Disease · 2020 · 16 citations · Full text

Medicine, Pathology, Pharmacology +17