Tian Guan

Discovery of a Potent and Oral Available Complex I OXPHOS Inhibitor That Abrogates Tumor Growth and Circumvents MEKi Resistance

Peng He, Juanjuan Feng, Xinting Xia et al. · Journal of Medicinal Chemistry · 2023 · 27 citations

Medicine, Oncology, Pharmacology +17

Mesothelin-targeted CAR-NK Cells Derived From Induced Pluripotent Stem Cells Have a High Efficacy in Killing Triple-negative Breast Cancer Cells as Shown in Several Preclinical Models

Mei Yang, Tian Guan, Chunfa Chen et al. · Journal of Immunotherapy · 2023 · 21 citations

Medicine, Cancer Biology, Oncology +17

CD22 is a potential target of CAR-NK cell therapy for esophageal squamous cell carcinoma

Tingdang Liu, Ximing Dai, Yien Xu et al. · Journal of Translational Medicine · 2023 · 15 citations · Full text

Medicine, Immunology, Oncology +13

Discovery of a Highly Potent and Selective MYOF Inhibitor with Improved Water Solubility for the Treatment of Gastric Cancer

Haijun Gu, Ting Zhang, Tian Guan et al. · Journal of Medicinal Chemistry · 2023 · 14 citations · Full text

Medicine, Oncology, Pharmacology +15

Efficacy of the induced pluripotent stem cell derived and engineered CD276-targeted CAR-NK cells against human esophageal squamous cell carcinoma

Xiaolan Lin, Tian Guan, Yien Xu et al. · Frontiers in Immunology · 2024 · 14 citations · Full text

Medicine, Immunology, Oncology +17