Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation

Debbie K. Goode, Nadine Obier, M. S. Vijayabaskar, +18

Developmental Cell

T cell activation via CD2 [T, gp50]: the role of accessory cells in activating resting T cells via CD2.

Stéphane Huet, Hiro Wakasugi, Ghislaine Sterkers, +4

The Journal of Immunology

Adaptive Immune SystemImmunologyImmunologic MechanismAntigen ProcessingCd4 T Cell Responses +15

Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers

Anuradha Illendula, Jane Gilmour, Jolanta Grembecka, +20

EBioMedicine

Repression of Interleukin-5 Transcription by the Glucocorticoid Receptor Targets GATA3 Signaling and Involves Histone Deacetylase Recruitment

Young‐Koo Jee, Jane Gilmour, Audrey Kelly, +7

Journal of Biological Chemistry

AsthmaLung InflammationT-regulatory CellImmunologyImmunologic Mechanism +21

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification

Jane Gilmour, Salam A. Assi, Ulrike Jaegle, +6

Development

Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fate

Nadine Obier, Pierre Cauchy, Salam A. Assi, +9

Development

Molecular RegulationCooperative BindingVascular Smooth MuscleCellular PhysiologyAngiogenesis +22

High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules

Paul D. Andrews, Melissa Becroft, Anders Aspegren, +13

Biochemical Journal

Pharmaceutical ScienceAdult Stem CellStem Cell BiologyChemical BiologyPharmaceutical Chemistry +26

Fibronectin is a TH1-specific molecule in human subjects

Hilary Sandig, Joanne McDonald, Jane Gilmour, +2

Journal of Allergy and Clinical Immunology

FibrosisProtein FunctionImmunologyPathologyHuman Subjects +2

Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone

Hilary Sandig, Joanne McDonald, Jane Gilmour, +2

Proceedings of the National Academy of Sciences

Pmch ExpressionDifferentiated Th2ImmunologyImmune RegulationImmunologic Mechanism +19

Robust hematopoietic specification requires the ubiquitous Sp1 and Sp3 transcription factors

Jane Gilmour, Leigh O’Connor, Christopher Middleton, +5

Epigenetics & Chromatin