21:I[432972,["/_next/static/chunks/bb923814e1f4d2e9.js","/_next/static/chunks/dd3ee9f5b7716ca6.js","/_next/static/chunks/4204a0ae82542ca8.js","/_next/static/chunks/1270dead247da766.js","/_next/static/chunks/6e1aa89a642f40be.js","/_next/static/chunks/2d7aa753e81324a8.js","/_next/static/chunks/8ffd0b71567920d8.js","/_next/static/chunks/67ea6dfd21f16c5f.js","/_next/static/chunks/24eb4379f68013fd.js","/_next/static/chunks/b8cd775ffdf935bd.js","/_next/static/chunks/983103cd9eb7b428.js","/_next/static/chunks/263f2cdcb9aa2341.js","/_next/static/chunks/294b9525248c8e5f.js"],"default"] 22:T47c,Polyglycerol, porphyrin-cored dendrimers were synthesized by the click reaction of azide-cored polyglycerol dendrons and octaazidoporphyrin 19. The dendrons were synthesized divergently starting with TBDPS protected allyl alcohol 2. Two, three and four cycles of dihydroxylation-allyl etherification gave dendrons [G-2.5] 6, [G-3.5] 8, [G-4.5] 11, with four, eight, and sixteen alkene groups, respectively. Dendron 11 was readily prepared on large scale with an overall yield of 45%. Dendron 8 was deprotected and converted to the corresponding alkyne - and azide-cored dendron 13 and 15 in 89% and 75% yield, respectively. Dendron 11 was deprotected and converted to the corresponding alkyne - and azide-cored dendron 16 and 18 in 68% and 24% yield, respectively. Both the [G-3.5]-azide 15 and [G-4.5]-azide 18 were separately "clicked" to polyalkyne core 19 via the Huisgen 1,3-dipolar cycloaddition to afford 20 and 21 in 65% and 66% yield, respectively. Dendrimer 21 has a MW ~ 16,000 and 128 peripheral alkene groups.23:T80e,

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1	Engineering	2	2	171
2	Biomedical Engineering	2	2	171
3	Medicine	1	1	161
4	Biophysics	1	1	161
5	Molecular Imaging	1	1	10

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