Richard Heath

Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells

Angela Woods, Kristina Dickerson, Richard Heath et al. · Cell Metabolism · 2005 · 1.4K citations · Full text

Molecular Physiology, Signal Transduction, Signaling Pathway +12

Structure of mammalian AMPK and its regulation by ADP

Bing Xiao, Matthew J. Sanders, E. Underwood et al. · Nature · 2011 · 906 citations · Full text

Mammalian Ampk, Molecular Physiology, Signal Transduction +7

Structural basis for AMP binding to mammalian AMP-activated protein kinase

Bing Xiao, Richard Heath, Peter Saiu et al. · Nature · 2007 · 574 citations

Signal Transduction, Molecular Physiology, Biochemistry +8

Structural basis of AMPK regulation by small molecule activators

Bing Xiao, Matthew J. Sanders, David Carmena et al. · Nature Communications · 2013 · 530 citations · Full text

Defining the Mechanism of Activation of AMP-activated Protein Kinase by the Small Molecule A-769662, a Member of the Thienopyridone Family

Matthew J. Sanders, Zahabia S. Ali, Bronwyn D. Hegarty et al. · Journal of Biological Chemistry · 2007 · 343 citations · Full text

Small Molecule A-769662, Molecular Biology, Cellular Physiology +19