Johanna Huchting

Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

Ashleigh Shannon, Barbara Selisko, Thi-Tuyet-Nhung Le et al. · Nature Communications · 2020 · 305 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase

Ashleigh Shannon, Barbara Selisko, NTT Le et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 113 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Prodrugs of the Phosphoribosylated Forms of Hydroxypyrazinecarboxamide Pseudobase T-705 and Its De-Fluoro Analogue T-1105 as Potent Influenza Virus Inhibitors

Johanna Huchting, Evelien Vanderlinden, Mathias Winkler et al. · Journal of Medicinal Chemistry · 2018 · 44 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Cell line-dependent activation and antiviral activity of T-1105, the non-fluorinated analogue of T-705 (favipiravir)

Johanna Huchting, Evelien Vanderlinden, Ria Van Berwaer et al. · Antiviral Research · 2019 · 38 citations

Life Sciences, Medicinal Chemistry, Pharmacology +15

Synthesis of T‐705‐Ribonucleoside and T‐705‐Ribonucleotide and Studies of Chemical Stability

Johanna Huchting, Mathias Winkler, Hiba Nasser et al. · ChemMedChem · 2017 · 33 citations

Pharmacy, Biochemistry, Medicinal Chemistry +17