Role of mammalian Mre11 in classical and alternative nonhomologous end joining

Anyong Xie, Amy Kwok, Ralph Scully

Nature Structural & Molecular Biology

Endocytic PathwayMolecular BiologyCellular BiologyMolecular GeneticsMammalian Mre11 +2

Distinct Roles of Chromatin-Associated Proteins MDC1 and 53BP1 in Mammalian Double-Strand Break Repair

Anyong Xie, Andrea J. Hartlerode, Manuel Stucki, +9

Molecular Cell

ChromatinGenome InstabilityDna DamageChromatin StructureChromatin Remodeling +9

RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci

Yiduo Hu, Ralph Scully, Bijan Sobhian, +3

Genes & Development

GeneticsGenomic MechanismMolecular BiologyEpigeneticsBrca1 Activity +15

Control of Sister Chromatid Recombination by Histone H2AX

Anyong Xie, Nadine Puget, In‐Bo Shim, +5

Molecular Cell

Histone ModificationsChromatinChromatin RemodelingNatural SciencesGenetics +7

ROS-Mediated Selective Killing Effect of Black Phosphorus: Mechanistic Understanding and Its Guidance for Safe Biomedical Applications

Na Kong, Xiaoyuan Ji, Junqing Wang, +8

Nano Letters

EngineeringLipid PeroxidationApoptosisCell DeathRedox Biology +19

PARP1-Driven Poly-ADP-Ribosylation Regulates BRCA1 Function in Homologous Recombination–Mediated DNA Repair

Yiduo Hu, Sarah A. Petit, Scott B. Ficarro, +10

Cancer Discovery

Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing

Tao Guo, Yi-Li Feng, Jingjing Xiao, +12

Genome biology

The mTOR–S6K pathway links growth signalling to DNA damage response by targeting RNF168

Xiaoduo Xie, Hongli Hu, Xinyuan Tong, +24

Nature Cell Biology

Mtor–s6k PathwaySignaling PathwayCell RegulationMolecular RegulationReceptor Tyrosine Kinase +6

BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids

Gurushankar Chandramouly, Amy Kwok, Bin Huang, +3

Nature Communications

ChromatinGenome InstabilityCytogeneticsMedicineGenetics +8

Akt-Mediated Phosphorylation of XLF Impairs Non-Homologous End-Joining DNA Repair

Pengda Liu, Wenjian Gan, Chunguang Guo, +9

Molecular Cell

Genome InstabilityCell RegulationAkt-mediated PhosphorylationMolecular BiologyMedicine +2