Metabolic Features of Mouse and Human Retinas: Rods versus Cones, Macula versus Periphery, Retina versus RPE

Bo Li, Ting Zhang, Wei Liu, +8

iScience

Human macular Müller cells rely more on serine biosynthesis to combat oxidative stress than those from the periphery

Ting Zhang, Ling Zhu, Michele C. Madigan, +7

eLife

Ocular DiseaseRetinaOphthalmologyBiochemistryPeripheral Retina +11

Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site

Qinhuai Lai, Yuxi Wang, Ruixue Wang, +12

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryMedicineColchicine Binding SiteNatural Sciences +5

Efficacy of Lenvatinib, a multitargeted tyrosine kinase inhibitor, on laser-induced CNV mouse model of neovascular AMD

Xian Wei, Ting Zhang, Yuqin Yao, +9

Experimental Eye Research

OphthalmologyMedicineReceptor Tyrosine KinaseNeovascular AmdVascular Biology +6

Transketolase in human Müller cells is critical to resist light stress through the pentose phosphate and NRF2 pathways

Yingying Chen, Ting Zhang, Shaoxue Zeng, +14

Redox Biology

Compritol solid lipid nanoparticle formulations enhance the protective effect of betulinic acid derivatives in human Müller cells against oxidative injury

Zhengqi Cheng, Yue Li, Ke Wang, +9

Experimental Eye Research

Lipid PreparationHuman Müller CellsMedicineLipid PeroxidationBetulinic Acid Derivatives +5

High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design

Qingjie Xiao, Ting Xue, Shuai Wen, +6

Biochemical and Biophysical Research Communications

X-ray CrystallographyDrug DesignMedicineNatural SciencesHigh-resolution X-ray Structure +5

Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration

Shaoxue Zeng, Ting Zhang, Yingying Chen, +14

Theranostics

Investigation of indoleamine 2,3-dioxygenase 1 expression in uveal melanoma

Chen Liang, Lanya Peng, Shaoxue Zeng, +6

Experimental Eye Research

PhotocarcinogenesisMelanomaIndoleamine 2,3-Dioxygenase 1DermatologyMedicine +1

Simvastatin protects photoreceptors from oxidative stress induced by all‐<scp><i>trans</i></scp>‐retinal, through the up‐regulation of interphotoreceptor retinoid binding protein

Ting Zhang, Mark C. Gillies, Ying Wang, +9

British Journal of Pharmacology