Mechanism of Enhanced Oral Absorption of Morin by Phospholipid Complex Based Self-Nanoemulsifying Drug Delivery System

Jinjie Zhang, Jianbo Li, Yuan Ju, +3

Molecular Pharmaceutics

Cell-based Drug DeliveryNanomedicineLipid PreparationEngineeringEnhanced Oral Absorption +10

A novel series of napabucasin derivatives as orally active inhibitors of signal transducer and activator of transcription 3 (STAT3)

Chungen Li, Caili Chen, Qi An, +6

European Journal of Medicinal Chemistry

Signal TransductionMedicineNapabucasin DerivativesMechanism Of ActionSignal Transducer +8

Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers <i>in Vitro</i> and <i>in Vivo</i>

Yuan Ju, Lihui He, Yuanzheng Zhou, +8

Journal of Medicinal Chemistry

Single‐Molecule Interaction of Peptides with a Biological Nanopore for Identification of Protease Activity

Ke Sun, Yuan Ju, Chuan Chen, +4

Small Methods

EngineeringPeptide EngineeringMolecular BiologyPeptide ScienceNanopore‐based Sensing Platform +19

Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis

Pingxian Liu, Yang Yang, Yuan Ju, +7

Bioorganic Chemistry

Pulmonary TuberculosisBiochemistryMedicineMycobacterium TuberculosisNovel Pyrrole Derivatives +7

Natural amino acid salt catalyzed aldol reactions of isatins with ketones: highly enantioselective construction of 3-alkyl-3-hydroxyindolin-2-ones

Chen Gong, Yuan Ju, Tao Yang, +5

Tetrahedron Asymmetry

EngineeringBiochemistryOrganic ChemistryAldol ReactionsEnantioselective Construction +6

Prediction of Synergistic Antibiotic Combinations by Graph Learning

Ji Lv, Guixia Liu, Yuan Ju, +2

Frontiers in Pharmacology

EngineeringInteraction NetworkNetwork AnalysisAntibiotic ResistanceLink Prediction +18

Discovery of hybrids of indolin-2-one and nitroimidazole as potent inhibitors against drug-resistant bacteria

Yuanzheng Zhou, Yuan Ju, Yang Yang, +5

The Journal of Antibiotics

MedicineAntibacterial AgentAntimicrobial ChemotherapyMicrobiologyPotent Inhibitors +6

Repurposing Napabucasin as an Antimicrobial Agent against Oral Streptococcal Biofilms

Xinyi Kuang, Tao Yang, Chenzi Zhang, +6

BioMed Research International

ACDB: An Antibiotic Combination DataBase

Ji Lv, Guixia Liu, Wenxuan Dong, +2

Frontiers in Pharmacology