Modulation of tryptophan catabolism by regulatory T cells

Francesca Fallarino, Ursula Grohmann, Kwang Woo Hwang, +7

Nature Immunology

Signal TransductionT-regulatory CellImmunologyRegulatory T CellsAutoimmunity +5

CTLA-4–Ig regulates tryptophan catabolism in vivo

Ursula Grohmann, Ciriana Orabona, Francesca Fallarino, +8

Nature Immunology

Signal TransductionCell SignalingImmunologyAntigen ProcessingCtla-4–ig Regulates +4

The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells

Francesca Fallarino, Ursula Grohmann, Sylvaine You, +10

The Journal of Immunology

T cell apoptosis by tryptophan catabolism

Francesca Fallarino, Ursula Grohmann, Carmine Vacca, +5

Cell Death and Differentiation

T-regulatory CellApoptosisImmunologyCell DeathAutoimmunity +6

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

Maria Teresa Pallotta, Ciriana Orabona, Claudia Volpi, +14

Nature Immunology

InflammationReductive StressLong-term ToleranceSignal TransductionRedox Regulator +10

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

Alban Bessede, Marco Gargaro, Maria Teresa Pallotta, +35

Nature

Disease MechanismMedicineImmunologyReceptor (Biochemistry)Mechanism Of Action +6

A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells

Giada Mondanelli, Roberta Bianchi, Maria Teresa Pallotta, +20

Immunity

Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

Ursula Grohmann, Claudia Volpi, Francesca Fallarino, +13

Nature Medicine

Signal TransductionAllergyAllergy MedicineMedicineImmunology +9

CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86

Ciriana Orabona, Ursula Grohmann, Maria Laura Belladonna, +9

Nature Immunology

InflammationAutoimmune DiseaseAdaptive Immune SystemImmunologyImmunologic Mechanism +10

IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production

Ursula Grohmann, Maria Laura Belladonna, Roberta Bianchi, +4

Immunity

InflammationCytokineSignal TransductionImmune Cell DevelopmentImmunology +8