Kathryn Pickup

Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity

Peter Ballard, James Yates, Zhenfan Yang et al. · Clinical Cancer Research · 2016 · 719 citations

Medicine, Oncology, Pharmacology +17

Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor

Paul A. Dickinson, Mireille Cantarini, J. Collier et al. · Drug Metabolism and Disposition · 2016 · 129 citations

Medicine, Pharmacokinetics, Pharmacology +17

Diclofenac metabolism in the mouse: Novel<i>in vivo</i>metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry

Sunil Sarda, Chris Page, Kathryn Pickup et al. · Xenobiotica · 2011 · 60 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism

Eleanor Q. Blatherwick, Gary J. Van Berkel, Kathryn Pickup et al. · Xenobiotica · 2011 · 41 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

The hepatic reductase null mouse as a model for exploring hepatic conjugation of xenobiotics: Application to the metabolism of diclofenac

Kathryn Pickup, Alex Gavin, Huw B. Jones et al. · Xenobiotica · 2011 · 21 citations

Pharmacy, Pharmacokinetics, Pharmacology +16