Ken Umehara

Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo

Katsunori Sasahara, Yoshihiko Shimokawa, Yukihiro Hirao et al. · Drug Metabolism and Disposition · 2015 · 92 citations

Medicine, Pharmacokinetics, Pharmacology +14

Metabolic Mechanism of Delamanid, a New Anti-Tuberculosis Drug, in Human Plasma

Yoshihiko Shimokawa, Katsunori Sasahara, Noriyuki Koyama et al. · Drug Metabolism and Disposition · 2015 · 47 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Delamanid Does Not Inhibit or Induce Cytochrome P450 Enzymes <i>in Vitro</i>

Yoshihiko Shimokawa, Katsunori Sasahara, Noriaki Yoda et al. · Biological and Pharmaceutical Bulletin · 2014 · 42 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Inhibition of Human Drug Metabolizing Cytochrome P450 by Buprenorphine.

Ken Umehara, Yoshihiko Shimokawa, Gohachiro Miyamoto · Biological and Pharmaceutical Bulletin · 2002 · 41 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Comparison of P450 Enzymes Between Cynomolgus Monkeys and Humans: P450 Identities, Protein Contents, Kinetic Parameters, and Potential for Inhibitory Profiles

Chie Emoto, Noriaki Yoda, Yasuhiro Uno et al. · Current Drug Metabolism · 2013 · 28 citations

Medicine, Pharmacology, Toxicology +17