Zhen‐Ke Deng

Predicting human intestinal absorption with modified random forest approach: a comprehensive evaluation of molecular representation, unbalanced data, and applicability domain issues

Ningning Wang, Chen Huang, Jie Dong et al. · RSC Advances · 2017 · 108 citations · Full text

Engineering, Hit Identification, Gastroenterology +28

Ensemble partial least squares regression for descriptor selection, outlier detection, applicability domain assessment, and ensemble modeling in QSAR/QSPR modeling

Dongsheng Cao, Zhen‐Ke Deng, Minfeng Zhu et al. · Journal of Chemometrics · 2017 · 33 citations

Engineering, Machine Learning, Feature Selection +23

Three-Level Hepatotoxicity Prediction System Based on Adverse Hepatic Effects

Lu Liu, Li Fu, Jinwei Zhang et al. · Molecular Pharmaceutics · 2018 · 31 citations

ADME properties evaluation in drug discovery: Prediction of plasma protein binding using NSGA-II combining PLS and consensus modeling

Ningning Wang, Zhen‐Ke Deng, Chen Huang et al. · Chemometrics and Intelligent Laboratory Systems · 2017 · 30 citations

Drug Target, Biochemistry, Medicine +9

Identification of a Novel Bcl-2 Inhibitor by Ligand-Based Screening and Investigation of Its Anti-cancer Effect on Human Breast Cancer Cells

Mei Wen, Zhen‐Ke Deng, Shilong Jiang et al. · Frontiers in Pharmacology · 2019 · 17 citations · Full text