Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with optimized single-molecule barcodes

Katsuyuki Shiroguchi, Tony Z. Jia, Peter A. Sims, +1

Proceedings of the National Academy of Sciences

EngineeringGeneticsMolecular BiologyTranscriptomics TechnologyGenomics +20

Membraneless polyester microdroplets as primordial compartments at the origins of life

Tony Z. Jia, Kuhan Chandru, Yayoi Hongo, +4

Proceedings of the National Academy of Sciences

Rapid RNA Exchange in Aqueous Two-Phase System and Coacervate Droplets

Tony Z. Jia, Christian Hentrich, Jack W. Szostak

Origins of Life and Evolution of Biospheres

Deciphering Biosignatures in Planetary Contexts

Marjorie A. Chan, Nancy W. Hinman, Sally L. Potter‐McIntyre, +18

Astrobiology

Liquid Crystal Coacervates Composed of Short Double-Stranded DNA and Cationic Peptides

Tommaso P. Fraccia, Tony Z. Jia

ACS Nano

Protein AssemblyPeptide EngineeringShort Double-stranded DnaMolecular BiologyProtein Phase Separation +15

ATP-independent reversal of a membrane protein aggregate by a chloroplast SRP subunit

Peera Jaru-Ampornpan, Kuang Shen, Quang Vinh Lam, +4

Nature Structural & Molecular Biology

Membrane FusionBiochemistryNatural SciencesMembrane TransportMolecular Biology +8

<i>N</i>-Carboxyanhydride-Mediated Fatty Acylation of Amino Acids and Peptides for Functionalization of Protocell Membranes

Enver Çagrı Izgü, Anders Björkbom, Neha P. Kamat, +4

Journal of the American Chemical Society

Polyesters as a Model System for Building Primitive Biologies from Non-Biological Prebiotic Chemistry

Kuhan Chandru, Irena Mamajanov, Henderson James Cleaves, +1

Life

Bioorganic ChemistryEngineeringBuilding Primitive BiologiesOrganic ChemistryChemical Biology +19

A general LC-MS-based RNA sequencing method for direct analysis of multiple-base modifications in RNA mixtures

Ning Zhang, Shundi Shi, Tony Z. Jia, +5

Nucleic Acids Research

EngineeringGeneticsMolecular BiologyDirect AnalysisTranscriptomics Technology +20

Oligoarginine peptides slow strand annealing and assist non-enzymatic RNA replication

Tony Z. Jia, Albert C. Fahrenbach, Neha P. Kamat, +2

Nature Chemistry

BiochemistryProtein FoldingNatural SciencesOligonucleotideDna Replication +4