Jacob B. Holmes

Atomic-resolution chemical characterization of (2x)72-kDa tryptophan synthase via four- and five-dimensional ¹ H-detected solid-state NMR

Alexander Klein, Petra Rovó, Varun V. Sakhrani et al. · Proceedings of the National Academy of Sciences · 2022 · 53 citations · Full text

Imaging active site chemistry and protonation states: NMR crystallography of the tryptophan synthase α-aminoacrylate intermediate

Jacob B. Holmes, Viktoriia Liu, Bethany G. Caulkins et al. · Proceedings of the National Academy of Sciences · 2022 · 44 citations · Full text

Mutation of βGln114 to Ala Alters the Stabilities of Allosteric States in Tryptophan Synthase Catalysis

Rittik K. Ghosh, E. Hilario, Viktoriia Liu et al. · Biochemistry · 2021 · 12 citations · Full text

Atomic-level structure of the amorphous drug atuliflapon <i>via</i> NMR crystallography

Jacob B. Holmes, Daria Torodii, M. Balodis et al. · Faraday Discussions · 2024 · 11 citations · Full text