Vindi M. Jayasinghe‐Arachchige

Heteromeric three-stranded coiled coils designed using a Pb(ii)(Cys)3 template mediated strategy

Audrey E. Tolbert, Catherine S. Ervin, Leela Ruckthong et al. · Nature Chemistry · 2020 · 48 citations · Full text

Life Sciences, Biomolecular Engineering, Molecular Biology +6

Degradation of a Main Plastic Pollutant Polyethylene Terephthalate by Two Distinct Proteases (Neprilysin and Cutinase-like Enzyme)

Qiaoyu Hu, Vindi M. Jayasinghe‐Arachchige, Rajeev Prabhakar · Journal of Chemical Information and Modeling · 2021 · 34 citations

Life Sciences, Biochemistry, Catalysis +16

Effect of Chemically Distinct Substrates on the Mechanism and Reactivity of a Highly Promiscuous Metallohydrolase

Gaurav Sharma, Vindi M. Jayasinghe‐Arachchige, Qiaoyu Hu et al. · ACS Catalysis · 2020 · 27 citations

Life Sciences, Biochemistry, Chemistry +17

Leveraging QM/MM and Molecular Dynamics Simulations to Decipher the Reaction Mechanism of the Cas9 HNH Domain to Investigate Off-Target Effects

Yazdan Maghsoud, Vindi M. Jayasinghe‐Arachchige, Pratibha Kumari et al. · Journal of Chemical Information and Modeling · 2023 · 26 citations

Life Sciences, Biology, Molecular Biology +13

Mechanisms of peptide and phosphoester hydrolysis catalyzed by two promiscuous metalloenzymes (insulin degrading enzyme and glycerophosphodiesterase) and their synthetic analogues

Qiaoyu Hu, Vindi M. Jayasinghe‐Arachchige, Gaurav Sharma et al. · Wiley Interdisciplinary Reviews Computational Molecular Science · 2020 · 25 citations

Life Sciences, Biochemistry, Biotechnology +17