Giovanni Monaco

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl

Giovanni Monaco, Elke Decrock, H Akl et al. · Cell Death and Differentiation · 2011 · 176 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16

The BH4 Domain of Anti-apoptotic Bcl-XL, but Not That of the Related Bcl-2, Limits the Voltage-dependent Anion Channel 1 (VDAC1)-mediated Transfer of Pro-apoptotic Ca2+ Signals to Mitochondria

Giovanni Monaco, Elke Decrock, Nir Arbel et al. · Journal of Biological Chemistry · 2015 · 130 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Induction of Ca2+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2–IP3 receptor interaction

Fei Zhong, Michael W. Harr, Geert Bultynck et al. · Blood · 2010 · 121 citations

Life Sciences, Cancer Biology, Cell Biology +14

IP₃Receptors, Mitochondria, and Ca²⁺Signaling: Implications for Aging

Jean-Paul Decuypere, Giovanni Monaco, Ludwig Missiaen et al. · Journal of Aging Research · 2011 · 116 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2

Haidar Akl, Giovanni Monaco, Rita La Rovere et al. · Cell Death and Disease · 2013 · 108 citations · Full text

Life Sciences, Molecular Biology, Oncology +16