Louisa Temme

Preclinical Evaluation of Benzazepine-Based PET Radioligands (<i>R</i>)- and (<i>S</i>)-¹¹C-Me-NB1 Reveals Distinct Enantiomeric Binding Patterns and a Tightrope Walk Between GluN2B- and σ₁-Receptor–Targeted PET Imaging

Adrienne Müller Herde, Stefanie D. Krämer, Jasmine Varisco et al. · Journal of Nuclear Medicine · 2019 · 32 citations · Full text

Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes

Benjamin J. Eduful, Sean O’Byrne, Louisa Temme et al. · Journal of Medicinal Chemistry · 2021 · 32 citations · Full text

Design, Synthesis, Pharmacological Evaluation and Docking Studies of GluN2B‐Selective NMDA Receptor Antagonists with a Benzo[7]annulen‐7‐amine Scaffold

Sandeep Gawaskar, Louisa Temme, Julian A. Schreiber et al. · ChemMedChem · 2017 · 27 citations

Comparative Pharmacological Study of Common NMDA Receptor Open Channel Blockers Regarding Their Affinity and Functional Activity toward GluN2A and GluN2B NMDA Receptors

Louisa Temme, Dirk Schepmann, Julian A. Schreiber et al. · ChemMedChem · 2018 · 25 citations

Synthesis and Pharmacological Evaluation of Enantiomerically Pure GluN2B Selective NMDA Receptor Antagonists

Frederik Börgel, Marina Szermerski, Julian A. Schreiber et al. · ChemMedChem · 2018 · 25 citations