Linnéa Garoff

Mutation supply and relative fitness shape the genotypes of ciprofloxacin-resistant <i>Escherichia coli</i>

Douglas L. Huseby, Franziska Pietsch, Gerrit Brandis et al. · Molecular Biology and Evolution · 2017 · 101 citations · Full text

E. Coli, Genetics, Escherichia Coli +21

Trypanothione Reductase: A Target Protein for a Combined In Vitro and In Silico Screening Approach

Beig Mathias, Frank Oellien, Linnéa Garoff et al. · PLoS neglected tropical diseases · 2015 · 64 citations · Full text

Drug Target, Hit Identification, Aldo-keto Reductase +26

Population Bottlenecks Strongly Influence the Evolutionary Trajectory to Fluoroquinolone Resistance in Escherichia coli

Linnéa Garoff, Franziska Pietsch, Douglas L. Huseby et al. · Molecular Biology and Evolution · 2020 · 52 citations · Full text

Experimental Evolution, Genetics, Escherichia Coli +16

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against <i>Acinetobacter baumannii</i> and <i>Pseudomonas aeruginosa</i>

Andrej Emanuel Cotman, Martina Durcik, Davide Benedetto Tiz et al. · Journal of Medicinal Chemistry · 2023 · 51 citations · Full text

Increased expression of Qnr is sufficient to confer clinical resistance to ciprofloxacin in Escherichia coli

Linnéa Garoff, Kavita Yadav, Diarmaid Hughes · Journal of Antimicrobial Chemotherapy · 2017 · 41 citations · Full text