Sharon Hulme

The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial

Navneet Singh, Stephen J. Hopkins, Sharon Hulme et al. · Journal of Neuroinflammation · 2014 · 288 citations · Full text

Medicine, Neurology, Neurosurgery +17

Brain inflammation is induced by co-morbidities and risk factors for stroke

Caroline Drake, Hervé Boutin, Matthew Jones et al. · Brain Behavior and Immunity · 2011 · 206 citations · Full text

Life Sciences, Neurology, Neuroscience +17

SCIL-STROKE (Subcutaneous Interleukin-1 Receptor Antagonist in Ischemic Stroke)

Craig J. Smith, Sharon Hulme, Andy Vail et al. · Stroke · 2018 · 195 citations · Full text

Life Sciences, Immunology, Pharmacotherapy +17

Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous Interleukin-1Ra in SAH (SCIL-SAH) study

James Galea, Kayode Ogungbenro, Sharon Hulme et al. · Journal of neurosurgery · 2017 · 128 citations · Full text

Medicine, Neurosurgery, Pharmacology +16

Intravenous Anakinra can Achieve Experimentally Effective Concentrations in the Central Nervous System within a Therapeutic Time Window: Results of a Dose-Ranging Study

James Galea, Kayode Ogungbenro, Sharon Hulme et al. · Journal of Cerebral Blood Flow & Metabolism · 2010 · 116 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17