Human Memory B Cells Harbor Diverse Cross-Neutralizing Antibodies against BK and JC Polyomaviruses

John M. Lindner, Vanessa Cornacchione, Atul Sathe, +11

Immunity

Humoral ResponseImmunologyAntiviral ResponseJc PolyomavirusesVirology +4

Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy

Chin Leng Tan, Katharina A.M. Lindner, Tamara Boschert, +13

Nature Biotechnology

Loss of immune tolerance to IL-2 in type 1 diabetes

Louis Pérol, John M. Lindner, Pamela Caudana, +20

Nature Communications

Synthetic Standards Combined With Error and Bias Correction Improve the Accuracy and Quantitative Resolution of Antibody Repertoire Sequencing in Human Naïve and Memory B Cells

Simon Friedensohn, John M. Lindner, Vanessa Cornacchione, +6

Frontiers in Immunology

Antigen Extraction and B Cell Activation Enable Identification of Rare Membrane Antigen Specific Human B Cells

Maria Zimmermann, Natalie Rose, John M. Lindner, +10

Frontiers in Immunology

HistocompatibilityAdaptive Immune SystemHumoral ResponseImmunologyAntigen Processing +16

Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis

Caterina E. Faliti, Maria Mesina, Jinyong Choi, +16

Immunity

InflammationCytokineAutoimmune DiseaseLymphocyte DevelopmentImmune Cell Development +8

T-FINDER: A highly sensitive, pan-HLA platform for functional T cell receptor and ligand discovery

Miray Cetin, Veronica Pinamonti, Theresa Schmid, +21

Science Advances

Class IiSensitive TcrT-regulatory CellImmunologyPathology +17

H3K27M neoepitope vaccination in diffuse midline glioma induces B and T cell responses across diverse HLA loci of a recovered patient

Tamara Boschert, Kristina Kromer, Taga Lerner, +12

Science Advances

Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE

Caterina E. Faliti, Trinh T. P. Van, Fabliha A. Anam, +27

Nature Immunology

Cutting Edge: The Transcription Factor Bob1 Counteracts B Cell Activation and Regulates miR-146a in B Cells

John M. Lindner, Hiroyuki Kayo, Sebastian Hedlund, +3

The Journal of Immunology

Humoral ResponseImmune RegulationImmunologyB Cell ActivationImmunotherapy +16