Mohammed H. Cherkaoui‐Rbati

A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria

Adoke Yeka, Rella Zoleko‐Manego, Serge Ouoba et al. · Malaria Journal · 2021 · 59 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

A Phase 1, Placebo-controlled, Randomized, Single Ascending Dose Study and a Volunteer Infection Study to Characterize the Safety, Pharmacokinetics, and Antimalarial Activity of the <i>Plasmodium</i> Phosphatidylinositol 4-Kinase Inhibitor MMV390048

James McCarthy, Cristina Donini, Stephan Chalon et al. · Clinical Infectious Diseases · 2020 · 55 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +14

The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to <i>Plasmodium falciparum</i> parasite resistance

James M. Murithi, Cécile Pascal, Jade Bath et al. · Science Translational Medicine · 2021 · 50 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Chemoprotective Antimalarial Activity of P218 against Plasmodium falciparum: A Randomized, Placebo-Controlled Volunteer Infection Study

Mohamed Farouk Chughlay, Myriam El Gaaloul, Cristina Donini et al. · American Journal of Tropical Medicine and Hygiene · 2021 · 32 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +15

The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of Plasmodium falciparum Viability after Antimalarial Treatment In Vitro

Annabelle Walz, Maëlle Duffey, Ghaith Aljayyoussi et al. · Pharmaceuticals · 2023 · 19 citations · Full text

Medicine, Infectious Diseases, Pharmacology +17