Efstathios S. Gonos

Postmitotic neurons develop a p21‐dependent senescence‐like phenotype driven by a DNA damage response

Diana Jurk, Chunfang Wang, Satomi Miwa et al. · Aging Cell · 2012 · 592 citations · Full text

Education, Neurobiology, Neuroscience +17

Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast

Patrick Dumont, Maggi Burton, Qin M. Chen et al. · Free Radical Biology and Medicine · 2000 · 368 citations

Life Sciences, Cell Biology, Molecular Biology +15

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

Niki Chondrogianni, Fiona L. L. Stratford, Ioannis P. Trougakos et al. · PubMed · 2003 · 329 citations

Life Sciences, Cell Biology, Molecular Biology +17

Overexpression of Proteasome β5 Assembled Subunit Increases the Amount of Proteasome and Confers Ameliorated Response to Oxidative Stress and Higher Survival Rates

Niki Chondrogianni, Christos Tzavelas, Alexander J. Pemberton et al. · Journal of Biological Chemistry · 2005 · 229 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Nuclear Erythroid Factor 2-mediated Proteasome Activation Delays Senescence in Human Fibroblasts

Suzanne Kapeta, Niki Chondrogianni, Efstathios S. Gonos · Journal of Biological Chemistry · 2010 · 227 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17