Identification and Biological Activity of the Active Metabolite of Clopidogrel

Pierre Savi, Jean‐Marie Pereillo, Marie-Françoise Uzabiaga, +5

Thrombosis and Haemostasis

Secondary MetabolitePharmacotherapyPolyphenolicsMedicinal ChemistryPlatelet Adp Receptor +15

The increase in urinary excretion of 6 beta‐hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction.

Cécile Ged, JM Rouillon, Lydiane Pichard, +6

British Journal of Clinical Pharmacology

Urinary ExcretionCortisol 6PharmacotherapyDaily ExcretionExperimental Pharmacology +20

Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily.

Jean Combalbert, Isabelle Fabre, G Fabre, +4

Drug Metabolism and Disposition

The Antiaggregating Activity of Clopidogrel Is due to a Metabolic Activation by the Hepatic Cytochrome P450-1A

Pierre Savi, Jean Combalbert, C Gaich, +4

Thrombosis and Haemostasis

Metabolic ActivationCytochrome P450 SubfamiliesImmunologyPathologyPharmacotherapy +20

Importance of hepatic metabolism in the antiaggregating activity of the thienopyridine clopidogrel

Pierre Savi, Jean‐Marc Herbert, A. M. Pflieger, +5

Biochemical Pharmacology

BiochemistryMedicineLiver PhysiologyPhysiologyHepatic Metabolism +9

Treatment of Menopausal Vasomotor Symptoms With Fezolinetant, a Neurokinin 3 Receptor Antagonist: A Phase 2a Trial

Herman Depypere, D. Timmerman, Gilbert Donders, +5

The Journal of Clinical Endocrinology & Metabolism

Characterization of midazolam metabolism using human hepatic musomal fractions and hepatocytes in suspension obtained by perfusing whole human livers

Gérard Fabre, Roger Rahmani, M. Placidi, +6

Biochemical Pharmacology

HepatologyWhole Human LiversMedicineLiver PhysiologyHepatotoxicity +5

The NK3 Receptor Antagonist ESN364 Suppresses Sex Hormones in Men and Women

Graeme L. Fraser, Steven Ramael, Hamid R. Hoveyda, +2

The Journal of Clinical Endocrinology & Metabolism

Randomized Controlled Trial of Neurokinin 3 Receptor Antagonist Fezolinetant for Treatment of Polycystic Ovary Syndrome

Graeme L. Fraser, Barbara Obermayer‐Pietsch, Joop S.E. Laven, +8

The Journal of Clinical Endocrinology & Metabolism

Ontogenesis of rabbit liver cytochrome <i>P</i>450

Claude BONFINS, Jean Combalbert, Thierry Pineau, +5

European Journal of Biochemistry