Brockman Rw

Implications of biochemical, cytokinetic, pharmacologic, and toxicologic relationships in the design of optimal therapeutic schedules.

Skipper He, Schabel Fm, Mellett Lb et al. · PubMed · 1970 · 285 citations

Molecular Pharmacology, Pharmacological Study, Optimal Therapeutic Schedules +6

Observations on the antileukemic activity of pyridine-2-carboxaldehyde thiosemicarbazone and thiocarbohydrazone.

Brockman Rw, Thomson, Bell Mj et al. · PubMed · 1956 · 179 citations

Molecular Pharmacology, Medicinal Chemistry, Bioorganic Chemistry +12

Structure-activity relationships observed on screening a series of pyrazolopyrimidines against experimental neoplasms.

Skipper He, Robins Rk, Thomson et al. · PubMed · 1957 · 64 citations

Pharmacotherapy, Chemical Biology, Pharmaceutical Chemistry +17

Resistance to purine antagonists in experimental leukemia systems.

Brockman Rw · PubMed · 1965 · 43 citations

Hematological Malignancy, Molecular Pharmacology, Nucleic Acid Chemistry +15

A quick reference chart on cross resistance between anticancer patients.

Skipper He, Hutchison Dj, Schabel Fm et al. · PubMed · 1972 · 13 citations

Cross Resistance, Oncology, Medicine +8