Irene A. Retmana

Variability of in vivo potency tests of Diphtheria, Tetanus and acellular Pertussis (DTaP) vaccines

Coen A.L. Stalpers, Irene A. Retmana, Jeroen L. A. Pennings et al. · Vaccine · 2021 · 24 citations · Full text

Vaccination, Vaccine Safety, Vaccinology +13

Quantification of KRAS inhibitor sotorasib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry

Irene A. Retmana, Nancy H.C. Loos, Alfred H. Schinkel et al. · Journal of Chromatography B · 2021 · 17 citations · Full text

P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) limit brain accumulation of the FLT3 inhibitor quizartinib in mice

Jing Wang, Changpei Gan, Irene A. Retmana et al. · International Journal of Pharmaceutics · 2018 · 13 citations · Full text

Medicine, Pharmacology, Flt3 Inhibitor Quizartinib +6

Liquid chromatography-tandem mass spectrometric assay for the quantitative determination of the tyrosine kinase inhibitor quizartinib in mouse plasma using salting-out liquid-liquid extraction

Irene A. Retmana, Jing Wang, Alfred H. Schinkel et al. · Journal of Chromatography B · 2017 · 11 citations · Full text

ABCB1 limits brain exposure of the KRASG12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability

Nancy H.C. Loos, Irene A. Retmana, Wenlong Li et al. · Pharmacological Research · 2022 · 11 citations · Full text

Whereas Abcb1, Medicine, Mechanism Of Action +10