A.M. Schumann

The pharmacokinetics and macromolecular interactions of perchloroethylene in mice and rats as related to oncogenicity

A.M. Schumann, J.F. Quast, P.G. Watanabe · Toxicology and Applied Pharmacology · 1980 · 119 citations

Macromolecular Interactions, Endocrine Disruptors, Medicine +8

Mutational analysis of the H-ras oncogene in spontaneous C57BL/6 x C3H/He mouse liver tumors and tumors induced with genotoxic and nongenotoxic hepatocarcinogens.

T Fox, A.M. Schumann, P.G. Watanabe et al. · PubMed · 1990 · 93 citations

Genetics, Pathology, H-ras Gene Activation +18

Physiologically based pharmacokinetic modeling with methylchloroform: implications for interspecies, high dose/low dose, and dose route extrapolations

Richard H. Reitz, James N. McDougal, Matthew W. Himmelstein et al. · Toxicology and Applied Pharmacology · 1988 · 86 citations

Pharmacokinetic Modeling, Pharmacodynamics, High Dose/low Dose +8

In Vivoandin VitroStudies of Perchloroethylene Metabolism for Physiologically Based Pharmacokinetic Modeling in Rats, Mice, and Humans

Richard H. Reitz, Michael L. Gargas, Alan L. Mendrala et al. · Toxicology and Applied Pharmacology · 1996 · 67 citations

Pharmacokinetic Modeling, Perchloroethylene Metabolism, Physiologically-based Pharmacokinetic Modeling +12

[14C]Methyl chloroform (1,1,1-trichloroethane): Pharmacokinetics in rats and mice following inhalation exposure

A.M. Schumann, T Fox, P.G. Watanabe · Toxicology and Applied Pharmacology · 1982 · 46 citations

Environmental Chemistry, Allergy, Respiratory Toxicology +11